4BTI
factor Xa in complex with the dual thrombin-FXa inhibitor 58.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, E) | COAGULATION FACTOR X HEAVY CHAIN | polymer | 96 | 10533.7 | 2 | UniProt (P00742) Pfam (PF00008) Pfam (PF14670) | HOMO SAPIENS (HUMAN) | STUART FACTOR, STUART-PROWER FACTOR ACTIVATED FACTOR XA HEAVY CHAIN |
| 2 | B, D (B, F) | COAGULATION FACTOR X LIGHT CHAIN | polymer | 254 | 28550.6 | 2 | UniProt (P00742) Pfam (PF00089) | HOMO SAPIENS (HUMAN) | STUART FACTOR, STUART-PROWER FACTOR, FACTOR X HEAVY CHAIN |
| 3 | E, G (B, F) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | F, H (B, F) | 5-Chloro-thiophene-2-carboxylic acid [(S)-2-[2-difluoromethoxy-3-(2-oxo-piperidin-1-yl)-benzenesulfonylamino]-3-((S)-3-dimethylamino-pyrrolidin-1-yl)-3-oxo-propyl]-amide | non-polymer | 648.1 | 2 | Chemie (7R9) | |||
| 5 | I, J, K, L (A, B, E, F) | water | water | 18.0 | 609 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 78168.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1376.4 | |
| All* | Total formula weight | 79545.1 |
