4BS2
NMR structure of human TDP-43 tandem RRMs in complex with UG-rich RNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TAR DNA-BINDING PROTEIN 43 | polymer | 174 | 19995.7 | 1 | UniProt (Q13148) Pfam (PF00076) | HOMO SAPIENS (HUMAN) | TDP-43, TDP-43 TANDEM RRMS |
| 2 | B (B) | 5'-R(*GP*UP*GP*UP*GP*AP*AP*UP*GP*AP*AP*UP)-3' | polymer | 12 | 3877.4 | 1 | HOMO SAPIENS | UG-RICH RNA |
Sequence modifications
A: 102 - 269 (UniProt: Q13148)
| PDB | External Database | Details |
|---|---|---|
| Gly 96 | - | expression tag |
| Ser 97 | - | expression tag |
| His 98 | - | expression tag |
| Met 99 | - | expression tag |
| Ala 100 | - | expression tag |
| Ser 101 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 23873.1 | |
| All* | Total formula weight | 23873.1 |
