4BQ8

Crystal structure of the RGMB-NEO1 complex form 3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	NEOGENIN	polymer	213	24076.3	1	UniProt (P97798) Pfam (PF00041)	MUS MUSCULUS (HOUSE MOUSE)
2	B (B)	RGM DOMAIN FAMILY MEMBER B	polymer	122	13318.7	1	UniProt (Q6NW40) Pfam (PF06535)	HOMO SAPIENS (HUMAN)	REPULSIVE GUIDANCE MOLECULE B, DRG11-RESPONSIVE AXONAL GUIDANCE AND OUTGROWTH OF NEURITE, DRAGON
3	C (C)	RGM DOMAIN FAMILY MEMBER B	polymer	251	27945.4	1	UniProt (Q6NW40) Pfam (PF06535) Pfam (PF06534)	HOMO SAPIENS (HUMAN)	REPULSIVE GUIDANCE MOLECULE B, DRG11-RESPONSIVE AXONAL GUIDANCE AND OUTGROWTH OF NEURITE, DRAGON
4	D (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
5	E, F, G (A, B, C)	water	water		18.0	15	Chemie (HOH)

Sequence modifications

A: 883 - 1083 (UniProt: P97798)

PDB	External Database	Details
Glu 880	-	expression tag
Thr 881	-	expression tag
Gly 882	-	expression tag
Gly 1084	-	expression tag
Thr 1085	-	expression tag
Lys 1086	-	expression tag
His 1087	-	expression tag
His 1088	-	expression tag
His 1089	-	expression tag
His 1090	-	expression tag
His 1091	-	expression tag
His 1092	-	expression tag

B: 50 - 168 (UniProt: Q6NW40)

PDB	External Database	Details
Glu 47	-	expression tag
Thr 48	-	expression tag
Gly 49	-	expression tag

C: 169 - 410 (UniProt: Q6NW40)

PDB	External Database	Details
Gly 411	-	expression tag
Thr 412	-	expression tag
Lys 413	-	expression tag
His 414	-	expression tag
His 415	-	expression tag
His 416	-	expression tag
His 417	-	expression tag
His 418	-	expression tag
His 419	-	expression tag
Gly 225	Glu 225	conflict

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	65340.4
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	65561.6

*Water molecules are not included.