4BNV

Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 1-(2-chlorophenyl)-3-(1- methylbenzimidazol-2-yl)urea at 2.5A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG	polymer	269	28168.0	4	UniProt (O54438) Pfam (PF13561) In PDB	PSEUDOMONAS AERUGINOSA	3-OXOACYL-ACYL-CARRIER-PROTEIN REDUCTASE, 3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE, BETA-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE, BETA-KETOACYL-ACP REDUCTASE, 3-OXOACYL-ACP REDUCTASE
2	B, D	1-(2-chlorophenyl)-3-(1-methylbenzimidazol-2-yl)urea	non-polymer		300.7	2	Chemie (Q7U)
3		water	water		18.0	57	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 247 (UniProt: O54438)

PDB	External Database	Details
Met -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
Ser -14	-	expression tag
Ser -13	-	expression tag
Gly -12	-	expression tag
Val -11	-	expression tag
Asp -10	-	expression tag
Leu -9	-	expression tag
Gly -8	-	expression tag
Thr -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	112671.8
Non-Polymers*	Number of molecules	2
	Total formula weight	601.5
All*	Total formula weight	113273.3

*Water molecules are not included.