4BL9
Crystal structure of full-length human Suppressor of fused (SUFU) mutant lacking a regulatory subdomain (crystal form I)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG | polymer | 756 | 84054.7 | 4 | UniProt (P0AEX9) UniProt (Q9UMX1) Pfam (PF01547) Pfam (PF05076) Pfam (PF12470) | ESCHERICHIA COLI | |
| 2 | E, F, G, H (E, F, G, H) | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 4 | In PDB BIRD (PRD_900001) GlyTouCan (G07411ON) | alpha-maltose |
Sequence modifications
A, B, C, D: 2 - 368 (UniProt: P0AEX9)
A, B, C, D: 372 - 618 (UniProt: Q9UMX1)
A, B, C, D: 626 - 748 (UniProt: Q9UMX1)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
| Thr 3 | Ile 28 | engineered mutation |
| Ala 360 | Glu 385 | engineered mutation |
| Ala 363 | Lys 388 | engineered mutation |
| Ala 364 | Asp 389 | engineered mutation |
| Asn 368 | Arg 393 | engineered mutation |
| Ala 369 | - | linker |
| Ala 370 | - | linker |
| Ala 371 | - | linker |
| Val 749 | - | expression tag |
| Glu 750 | - | expression tag |
| His 751 | - | expression tag |
| His 752 | - | expression tag |
| His 753 | - | expression tag |
| His 754 | - | expression tag |
| His 755 | - | expression tag |
| His 756 | - | expression tag |
A, B, C, D: 626 - 748 (UniProt: Q9UMX1)
| PDB | External Database | Details |
|---|---|---|
| Pro 619 | - | linker |
| Ser 620 | - | linker |
| Arg 621 | - | linker |
| Gly 622 | - | linker |
| Glu 623 | - | linker |
| Asp 624 | - | linker |
| Pro 625 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 336218.9 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1369.2 | |
| All* | Total formula weight | 337588.1 |
