4BL3
Crystal structure of PBP2a clinical mutant N146K from MRSA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PENICILLIN BINDING PROTEIN 2 PRIME | polymer | 640 | 73143.6 | 2 | UniProt (Q54113) Pfam (PF05223) Pfam (PF03717) Pfam (PF00905) UniProt (by SIFTS) (A0A0H3JPA5) | STAPHYLOCOCCUS AUREUS | PENICILLIN-BINDING PROTEIN 2A |
| 2 | C, D, E, F, J... (A, B) | CADMIUM ION | non-polymer | 112.4 | 7 | Chemie (CD) | |||
| 3 | G, H, M, N (A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 4 | I, O (A, B) | beta-muramic acid | non-polymer | 251.2 | 2 | Chemie (MUR) | |||
| 5 | P, Q (A, B) | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence modifications
A, B: 26 - 668 (UniProt: Q54113)
| PDB | External Database | Details |
|---|---|---|
| Lys 146 | Asn 146 | engineered mutation |
| - | Glu 609 | deletion |
| - | Thr 610 | deletion |
| - | Gly 611 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 146287.3 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1431.2 | |
| All* | Total formula weight | 147718.4 |
