4BL3
Crystal structure of PBP2a clinical mutant N146K from MRSA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PENICILLIN BINDING PROTEIN 2 PRIME | polymer | 640 | 73143.6 | 2 | UniProt (Q54113) UniProt (by SIFTS) (A0A0H3JPA5) | STAPHYLOCOCCUS AUREUS | PENICILLIN-BINDING PROTEIN 2A |
| 2 | C, D, E, F, J... (A, B) | CADMIUM ION | non-polymer | 112.4 | 7 | Chemie (CD) PubChem (31193) | |||
| 3 | G, H, M, N (A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) PubChem (312) | |||
| 4 | I, O (A, B) | beta-muramic acid | non-polymer | 251.2 | 2 | Chemie (MUR) PubChem (16219635) PubChem (40488267) PubChem (45039974) PubChem (46782404) PubChem (92274510) PubChem (92274511) PubChem (92274512) PubChem (92274513) PubChem (124922340) PubChem (124922342) PubChem (126968561) PubChem (129696424) PubChem (140369008) PubChem (141806625) PubChem (141808570) PubChem (156619036) PubChem (176059267) PubChem (22833605) PubChem (92146549) PubChem (9816401) PubChem (124922341) PubChem (433580) PubChem (441038) PubChem (446972) PubChem (6452113) PubChem (7058068) PubChem (12313001) | |||
| 5 | P, Q (A, B) | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence modifications
A, B: 26 - 668 (UniProt: Q54113)
| PDB | External Database | Details |
|---|---|---|
| Lys 146 | Asn 146 | engineered mutation |
| - | Glu 609 | deletion |
| - | Thr 610 | deletion |
| - | Gly 611 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 146287.3 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1431.2 | |
| All* | Total formula weight | 147718.4 |
