4BIS
JMJD2A COMPLEXED WITH 8-HYDROXYQUINOLINE-4-CARBOXYLIC ACID
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | LYSINE-SPECIFIC DEMETHYLASE 4A | polymer | 381 | 44326.3 | 2 | UniProt (O75164) Pfam (PF02375) Pfam (PF02373) | HOMO SAPIENS (HUMAN) | JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 3A, JUMONJI DOMAIN-CONTAINING PROTEIN 2A |
| 2 | C, H (A, B) | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
| 3 | D, I (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, J (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | F, K (A, B) | 8-hydroxyquinoline-4-carboxylic acid | non-polymer | 189.2 | 2 | Chemie (8HQ) | |||
| 6 | G (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | L, M (A, B) | water | water | 18.0 | 263 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 359 (UniProt: O75164)
| PDB | External Database | Details |
|---|---|---|
| Met -21 | - | expression tag |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| Ser -14 | - | expression tag |
| Ser -13 | - | expression tag |
| Gly -12 | - | expression tag |
| Val -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Leu -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Thr -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 88652.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 789.5 | |
| All* | Total formula weight | 89442.1 |
