4BD0
X-ray structure of a perdeuterated Toho-1 R274N R276N double mutant Beta-lactamase in complex with a fully deuterated boronic acid (BZB)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | BETA-LACTAMASE TOHO-1 | polymer | 261 | 28104.7 | 1 | UniProt (Q47066) Pfam (PF00144) Pfam (PF00905) Pfam (PF13354) In PDB | ESCHERICHIA COLI BL21 | |
| 2 | A | BENZO[B]THIOPHENE-2-BORONIC ACID | non-polymer | 178.0 | 1 | Chemie (BZB) | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 4 | water | water | 18.0 | 397 | Chemie (HOH) |
Sequence modifications
A: 27 - 290 (UniProt: Q47066)
| PDB | External Database | Details |
|---|---|---|
| Asn 274 | Arg 275 | engineered mutation |
| Asn 276 | Arg 277 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28104.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 754.4 | |
| All* | Total formula weight | 28859.1 |
