4BCW
Carbonic anhydrase IX mimic in complex with (E)-2-(5-bromo-2- hydroxyphenyl)ethenesulfonic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CARBONIC ANHYDRASE 2 | polymer | 257 | 28962.7 | 1 | UniProt (P00918) Pfam (PF00194) | HOMO SAPIENS (HUMAN) | CARBONATE DEHYDRATASE II, CARBONIC ANHYDRASE C, CAC, CARBONIC ANHYDRASE II, CA-II |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | (E)-2-(5-BROMO-2-HYDROXYPHENYL)ETHENESULFONIC ACID | non-polymer | 279.1 | 1 | Chemie (TU0) | |||
| 4 | D (A) | water | water | 18.0 | 238 | Chemie (HOH) |
Sequence modifications
A: 4 - 261 (UniProt: P00918)
| PDB | External Database | Details |
|---|---|---|
| Ser 65 | Ala 65 | engineered mutation |
| Gln 67 | Asn 67 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28962.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 344.5 | |
| All* | Total formula weight | 29307.2 |
