4BC6

Crystal structure of human serine threonine kinase-10 bound to novel Bosutinib Isoform 1, previously thought to be Bosutinib

Replaces:  3ZZ2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	SERINE/THREONINE-PROTEIN KINASE 10	polymer	293	33128.3	1	UniProt (O94804) Pfam (PF00069) In PDB	HOMO SAPIENS (HUMAN)	SERINE THREONINE KINASE-10, LYMPHOCYTE-ORIENTED KINASE
2	A	4-[(3,5-DICHLORO-4-METHOXYPHENYL)AMINO]-6-METHOXY-7-[3-(4-METHYLPIPERAZIN-1-YL)PROPOXY]QUINOLINE-3-CARBONITRILE	non-polymer		530.4	1	Chemie (XZN)
3	A	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
4		water	water		18.0	44	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	33128.3
Non-Polymers*	Number of molecules	2
	Total formula weight	592.5
All*	Total formula weight	33720.8

*Water molecules are not included.