4BC6
Crystal structure of human serine threonine kinase-10 bound to novel Bosutinib Isoform 1, previously thought to be Bosutinib
Replaces: 3ZZ2Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SERINE/THREONINE-PROTEIN KINASE 10 | polymer | 293 | 33128.3 | 1 | UniProt (O94804) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | SERINE THREONINE KINASE-10, LYMPHOCYTE-ORIENTED KINASE |
| 2 | B (A) | 4-[(3,5-DICHLORO-4-METHOXYPHENYL)AMINO]-6-METHOXY-7-[3-(4-METHYLPIPERAZIN-1-YL)PROPOXY]QUINOLINE-3-CARBONITRILE | non-polymer | 530.4 | 1 | Chemie (XZN) | |||
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D (A) | water | water | 18.0 | 44 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33128.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 592.5 | |
| All* | Total formula weight | 33720.8 |
