4BBR

Structure of RNA polymerase II-TFIIB complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1	polymer	1733	191821.6	1	UniProt (P04050) Pfam (PF04997) Pfam (PF05001) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) Pfam (PF04992) Pfam (PF04990) In PDB	SACCHAROMYCES CEREVISIAE	RPB1, RNA POLYMERASE II SUBUNIT 1, RNA POLYMERASE II SUBUNIT B1, DNA-DIRECTED RNA POLYMERASE III LARGEST SUBUNIT, RNA POLYMERASE II SUBUNIT B220
2	B	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2	polymer	1224	138937.3	1	UniProt (P08518) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) In PDB	SACCHAROMYCES CEREVISIAE	RPB2, RNA POLYMERASE II SUBUNIT 2, B150, DNA-DIRECTED RNA POLYMERASE II 140 KDA POLYPEPTIDE
3	C	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3	polymer	318	35330.5	1	UniProt (P16370) Pfam (PF01193) Pfam (PF01000) In PDB	SACCHAROMYCES CEREVISIAE	RPB3, RNA POLYMERASE II SUBUNIT 3, RNA POLYMERASE II SUBUNIT B3, B44.5, DNA-DIRECTED RNA POLYMERASE II 45 KDA POLYPEPTIDE
4	D	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4	polymer	221	25451.2	1	UniProt (P20433) Pfam (PF03874) In PDB	SACCHAROMYCES CEREVISIAE	RPB4, RNA POLYMERASE II SUBUNIT B4, B32, DNA-DIRECTED RNA POLYMERASE II 32 KDA POLYPEPTIDE
5	E	DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1	polymer	215	25117.1	1	UniProt (P20434) Pfam (PF03871) Pfam (PF01191) In PDB	SACCHAROMYCES CEREVISIAE	RPB5, RNA POLYMERASES I\,II\,AND III SUBUNIT ABC1, ABC27, DNA-DIRECTED RNA POLYMERASES I\,II\,AND III 27 KDA POLYPEPTIDE
6	F	DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2	polymer	155	17931.8	1	UniProt (P20435) Pfam (PF01192) In PDB	SACCHAROMYCES CEREVISIAE	RPB6, RNA POLYMERASES I\,II\,AND III SUBUNIT ABC2, ABC23, DNA-DIRECTED RNA POLYMERASES I\,II\,AND III 23 KDA POLYPEPTIDE
7	G	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7	polymer	171	19081.1	1	UniProt (P34087) Pfam (PF03876) Pfam (PF00575) In PDB	SACCHAROMYCES CEREVISIAE	RPB7, RNA POLYMERASE II SUBUNIT B7, B16
8	H	DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3	polymer	146	16525.4	1	UniProt (P20436) Pfam (PF03870) In PDB	SACCHAROMYCES CEREVISIAE	RPB8, RNA POLYMERASES I\,II\,AND III SUBUNIT ABC3, ABC14.4, ABC14.5, DNA-DIRECTED RNA POLYMERASES I\,II\,AND III 14.5 KDA POLYPEPTIDE
9	I	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9	polymer	122	14308.2	1	UniProt (P27999) Pfam (PF02150) Pfam (PF01096) In PDB	SACCHAROMYCES CEREVISIAE	RPB9, RNA POLYMERASE II SUBUNIT B9, B12.6, DNA-DIRECTED RNA POLYMERASE II 14.2 KDA POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II SUBUNIT 9
10	J	DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5	polymer	70	8290.7	1	UniProt (P22139) Pfam (PF01194) In PDB	SACCHAROMYCES CEREVISIAE	RPB10, RNA POLYMERASES I, II, AND III SUBUNIT ABC5, ABC10-BETA, ABC8, DNA-DIRECTED RNA POLYMERASES I, II, AND III 8.3 KDA POLYPEPTIDE
11	K	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11	polymer	120	13633.5	1	UniProt (P38902) Pfam (PF13656) Pfam (PF01193) In PDB	SACCHAROMYCES CEREVISIAE	RPB11, RNA POLYMERASE II SUBUNIT B11, B13.6, DNA-DIRECTED RNA POLYMERASE II 13.6 KDA POLYPEPTIDE
12	L	DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4	polymer	70	7730.0	1	UniProt (P40422) Pfam (PF03604) In PDB	SACCHAROMYCES CEREVISIAE	RPB12, RNA POLYMERASES I, II, AND III SUBUNIT ABC4, ABC10-ALPHA
13	M	TRANSCRIPTION INITIATION FACTOR IIB	polymer	345	38257.3	1	UniProt (P29055) Pfam (PF08271) Pfam (PF00382) In PDB	SACCHAROMYCES CEREVISIAE	TFIIB, GENERAL TRANSCRIPTION FACTOR TFIIB, TRANSCRIPTION FACTOR E
14	A, B, C, I, J...	ZINC ION	non-polymer		65.4	9	Chemie (ZN)
15	A	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)

Contents of the asymmetric unit

Polymers	Number of chains	13
	Total formula weight	552415.6
Non-Polymers*	Number of molecules	11
	Total formula weight	637.3
All*	Total formula weight	553052.9

*Water molecules are not included.