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4BBG

Crystal structure of human kinesin Eg5 in complex with 3-(((2-Aminoethyl)sulfanyl)(3-ethylphenyl) phenylmethyl)phenol

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
KINESIN-LIKE PROTEIN KIF11polymer36841055.61UniProt (P52732)
Pfam (PF00225)
HOMO SAPIENS (HUMAN)KINESIN-LIKE PROTEIN 1, KINESIN-LIKE SPINDLE PROTEIN HKSP, KINESIN-RELATED MOTOR PROTEIN EG5, THYROID RECEPTOR-INTERACTING PROTEIN 5, TR-INTERACTING PROTEIN 5, TRIP-5
2B
(A)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
3C
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4D, E, F, H, I
(A)
CHLORIDE IONnon-polymer35.55Chemie (CL)
5G
(A)
3-[(R)-2-azanylethylsulfanyl-(3-ethylphenyl)-phenyl-methyl]phenolnon-polymer363.51Chemie (V02)
6J
(A)
waterwater18.093Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41055.6
Non-Polymers*Number of molecules8
Total formula weight992.3
All*Total formula weight42047.9
*Water molecules are not included.

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