4BAK
Thrombin in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | THROMBIN LIGHT CHAIN | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) | HOMO SAPIENS (HUMAN) | COAGULATION FACTOR II |
| 2 | B (B) | THROMBIN HEAVY CHAIN | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) | HOMO SAPIENS (HUMAN) | COAGULATION FACTOR II |
| 3 | C (D) | HIRUDIN VARIANT-1 | polymer | 12 | 1463.5 | 1 | UniProt (P01050) | HIRUDO MEDICINALIS | HIRUDIN-1, HIRUDIN-I, LEPIRUDIN |
| 4 | D (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | E (B) | (2S)-N-(4-CARBAMIMIDOYLBENZYL)-1-[(2R)-2-CYCLOHEXYL-2-{[2-OXO-2-(PROPYLAMINO)ETHYL]AMINO}ACETYL]AZETIDINE-2-CARBOXAMIDE | non-polymer | 470.6 | 1 | Chemie (M67) | |||
| 6 | F, G (B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 7 | H, I, J (A, B, D) | water | water | 18.0 | 330 | Chemie (HOH) |
Sequence modifications
D: 353 - 364 (UniProt: P01050)
| PDB | External Database | Details |
|---|---|---|
| Gly 361 | Glu 61 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 35340.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 737.8 | |
| All* | Total formula weight | 36078.0 |
