4B99
Crystal Structure of MAPK7 (ERK5) with inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | MITOGEN-ACTIVATED PROTEIN KINASE 7 | polymer | 398 | 45003.6 | 1 | UniProt (Q13164) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | MAP KINASE 7, MAPK 7, BIG MAP KINASE 1, BMK-1, EXTRACELLULAR SIGNAL-REGULATED KINASE 5, ERK-5 |
2 | A | 11-cyclopentyl-2-[[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]carbonyl-phenyl]amino]-5-methyl-pyrimido[4,5-b][1,4]benzodiazepin-6-one | non-polymer | 624.8 | 1 | Chemie (R4L) | |||
3 | water | water | 18.0 | 9 | Chemie (HOH) |
Sequence modifications
A: 1 - 397 (UniProt: Q13164)
PDB | External Database | Details |
---|---|---|
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 45003.6 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 624.8 | |
All* | Total formula weight | 45628.4 |