4B7R
H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | NEURAMINIDASE | polymer | 387 | 42640.6 | 4 | UniProt (C7FH46) Pfam (PF00064) | INFLUENZA A VIRUS (A/CALIFORNIA/07/2009(H1N1)) | |
| 2 | E (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | AA, BA, F, G, L... (D, A, B, C) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 4 | CA, H, N, U (D, A, B, C) | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | non-polymer | 284.4 | 4 | Chemie (G39) | |||
| 5 | DA, I, O, V (D, A, B, C) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 4 | Chemie (EPE) | |||
| 6 | EA, FA, GA, J, K... (D, A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) | |||
| 7 | HA, IA, JA, KA (A, B, C, D) | water | water | 18.0 | 956 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 83 - 469 (UniProt: C7FH46)
| PDB | External Database | Details |
|---|---|---|
| Phe 351 | Tyr 351 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 170562.2 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 5065.7 | |
| All* | Total formula weight | 176052.3 |
