4B7R
H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | NEURAMINIDASE | polymer | 387 | 42640.6 | 4 | UniProt (C7FH46) | INFLUENZA A VIRUS (A/CALIFORNIA/07/2009(H1N1)) | |
| 2 | E (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | AA, BA, F, G, L... (D, A, B, C) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) PubChem (271) | |||
| 4 | CA, H, N, U (D, A, B, C) | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | non-polymer | 284.4 | 4 | Chemie (G39) PubChem (40640967) PubChem (40640969) PubChem (40640971) PubChem (44345914) PubChem (40640973) PubChem (58753598) PubChem (71038155) PubChem (71065667) PubChem (449381) PubChem (4631786) PubChem (95162772) PubChem (121452907) PubChem (124637832) PubChem (129886749) PubChem (134694948) PubChem (137378365) | |||
| 5 | DA, I, O, V (D, A, B, C) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 4 | Chemie (EPE) PubChem (23831) | |||
| 6 | EA, FA, GA, J, K... (D, A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) | |||
| 7 | HA, IA, JA, KA (A, B, C, D) | water | water | 18.0 | 956 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 83 - 469 (UniProt: C7FH46)
| PDB | External Database | Details |
|---|---|---|
| Phe 351 | Tyr 351 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 170562.2 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 5065.7 | |
| All* | Total formula weight | 176052.3 |
