4B7Q
H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | NEURAMINIDASE | polymer | 469 | 51638.7 | 4 | UniProt (C7FH46) Pfam (PF00064) | INFLUENZA A VIRUS (A/CALIFORNIA/07/2009(H1N1)) | |
| 2 | E, I, J, M, N... (A, B, C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) | |||
| 3 | F, K, P, T (A, B, C, D) | ZANAMIVIR | non-polymer | 332.3 | 4 | Chemie (ZMR) | |||
| 4 | G, H, L, Q, U (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 5 | V, W, X, Y (A, B, C, D) | water | water | 18.0 | 386 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 469 (UniProt: C7FH46)
| PDB | External Database | Details |
|---|---|---|
| Phe 351 | Tyr 351 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 206554.7 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 3299.3 | |
| All* | Total formula weight | 209854.0 |
