4B5W
Crystal structures of divalent metal dependent pyruvate aldolase R70A mutant, HpaI, in complex with pyruvate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | 4-HYDROXY-2-OXO-HEPTANE-1,7-DIOATE ALDOLASE | polymer | 256 | 27366.1 | 6 | UniProt (B1IS70) Pfam (PF03328) | ESCHERICHIA COLI ATCC 8739 | HPAI, 2,4-DIHYDROXYHEPT-2-ENE-1,7-DIOIC ACID ALDOLASE, HHED ALDOLASE, 4-HYDROXY-2-KETOHEPTANE-1,7-DIOATE ALDOLASE, HKHD ALDOLASE |
| 2 | G, J, L, O, R... (A, B, C, D, E...) | COBALT (II) ION | non-polymer | 58.9 | 6 | Chemie (CO) | |||
| 3 | H, M, P, S, V (A, C, D, E, F) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 4 | I, K, N, Q, T... (A, B, C, D, E...) | PYRUVIC ACID | non-polymer | 88.1 | 6 | Chemie (PYR) | |||
| 5 | AA, BA, CA, X, Y... (D, E, F, A, B...) | water | water | 18.0 | 1858 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 256 (UniProt: B1IS70)
| PDB | External Database | Details |
|---|---|---|
| Ala 70 | Arg 70 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 164196.9 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1082.4 | |
| All* | Total formula weight | 165279.2 |
