4B4W
Crystal structure of Acinetobacter baumannii N5, N10- methylenetetrahydrofolate dehydrogenase-cyclohydrolase (FolD) complexed with NADP cofactor and an inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | BIFUNCTIONAL PROTEIN FOLD | polymer | 303 | 32146.0 | 2 | UniProt (D0CBC8) Pfam (PF00763) Pfam (PF02882) In PDB | ACINETOBACTER BAUMANNII ATCC 19606 | N5, N10-METHYLENETETRAHYDROFOLATE DEHYDROGENASE-CYCLOHYDROLASE |
2 | A, B | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
3 | A, B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
4 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
5 | A, B | (2S)-2-[[4-[[2,4-bis(azanyl)-6-oxidanylidene-1H-pyrimidin-5-yl]carbamoylamino]phenyl]carbonylamino]pentanedioic acid | non-polymer | 433.4 | 2 | Chemie (9L9) | |||
6 | water | water | 18.0 | 592 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 282 (UniProt: D0CBC8)
PDB | External Database | Details |
---|---|---|
Met -20 | - | expression tag |
Gly -19 | - | expression tag |
Ser -18 | - | expression tag |
Ser -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
Ser -10 | - | expression tag |
Ser -9 | - | expression tag |
Gly -8 | - | expression tag |
Glu -7 | - | expression tag |
Asn -6 | - | expression tag |
Leu -5 | - | expression tag |
Tyr -4 | - | expression tag |
Phe -3 | - | expression tag |
Gln -2 | - | expression tag |
Gly -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 64292.0 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 2573.2 | |
All* | Total formula weight | 66865.2 |