4B3I
Crystal structure of Mycobacterium tuberculosis fatty acid beta- oxidation complex with CoenzymeA bound at the hydratase active sites
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | FATTY ACID BETA-OXIDATION COMPLEX ALPHA-CHAIN FADB | polymer | 736 | 78005.8 | 2 | UniProt (O53872) Pfam (PF00378) Pfam (PF02737) Pfam (PF00725) In PDB | MYCOBACTERIUM TUBERCULOSIS | ENOYLCOA HYDRATASE, HYDROXYACYLCOA DEHYDROGENASE, PROBABLE FATTY OXIDATION PROTEIN FADB |
| 2 | C, D | FATTY ACID BETA-OXIDATION COMPLEX BETA-CHAIN FADA | polymer | 403 | 42460.4 | 2 | UniProt (O53871) Pfam (PF00108) Pfam (PF02803) In PDB | MYCOBACTERIUM TUBERCULOSIS | THIOLASE, PUTATIVE ACYLTRANSFERASE RV0859 |
| 3 | C, A, D, B | SULFATE ION | non-polymer | 96.1 | 32 | Chemie (SO4) | |||
| 4 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | A, B | COENZYME A | non-polymer | 767.5 | 2 | Chemie (COA) | |||
| 6 | C, A | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 7 | water | water | 18.0 | 779 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 720 (UniProt: O53872)
| PDB | External Database | Details |
|---|---|---|
| Met -15 | - | expression tag |
| Gly -14 | - | expression tag |
| Ser -13 | - | expression tag |
| Ser -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Gln -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 240932.3 | |
| Non-Polymers* | Number of molecules | 39 |
| Total formula weight | 5739.8 | |
| All* | Total formula weight | 246672.1 |
