4B1U

Structure of the Phactr1 RPEL domain and RPEL motif directed assemblies with G-actin reveal the molecular basis for actin binding cooperativity.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	ACTIN, ALPHA SKELETAL MUSCLE	polymer	376	41965.8	1	UniProt (P68134) Pfam (PF00022)	ORYCTOLAGUS CUNICULUS (RABBIT)	ALPHA-ACTIN-1
2	B (M)	PHOSPHATASE AND ACTIN REGULATOR 1	polymer	32	3842.5	1	UniProt (G5E8P7) Pfam (PF02755) UniProt (by SIFTS) (Q2M3X8)	ORYCTOLAGUS CUNICULUS	PHOSPHATASE AND ACTIN REGULATOR 1\, ISOFORM CRA_C
3	C (B)	LATRUNCULIN B	non-polymer		395.5	1	Chemie (LAB) PubChem (3892) PubChem (72940) PubChem (5352046) PubChem (5353712) PubChem (6436219) PubChem (10000783) PubChem (14504487) PubChem (16760044) PubChem (20054954) PubChem (22832299) PubChem (23424960) PubChem (23863831) PubChem (25215545) PubChem (56928133) PubChem (98044135) PubChem (57370013) PubChem (162928966) PubChem (59169653) PubChem (59431496) PubChem (67441199) PubChem (67441200) PubChem (88895461) PubChem (90912141) PubChem (92209860) PubChem (98044136) PubChem (98044137) PubChem (129388766) PubChem (129388767) PubChem (146159701) PubChem (154825202) PubChem (162928961) PubChem (162928962) PubChem (162928963) PubChem (162928964) PubChem (162928965) PubChem (162928967) PubChem (163195209) PubChem (168317464) PubChem (171039486)
4	D (B)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	1	Chemie (ATP)
5	E (B)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG) PubChem (888)
6	F (B)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS) PubChem (3777159)
7	G (M)	CALCIUM ION	non-polymer		40.1	1	Chemie (CA) PubChem (271)
8	H, I (B, M)	water	water		18.0	155	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45808.2
Non-Polymers*	Number of molecules	5
	Total formula weight	1089.2
All*	Total formula weight	46897.5

*Water molecules are not included.