4AZH

Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	BETA-N-ACETYLHEXOSAMINIDASE	polymer	443	49790.9	4	UniProt (P49610) Pfam (PF00728) In PDB	STREPTOCOCCUS PNEUMONIAE	GLYCOSIDE HYDROLASE 20
2	A, B, C, D	N-acetylglucosaminono-1,5-lactone (Z)-oxime	non-polymer		234.2	4	Chemie (LOG)
3	A, B, C	1,2-ETHANEDIOL	non-polymer		62.1	12	Chemie (EDO)
4		water	water		18.0	1293	Chemie (HOH)

Sequence modifications

A, B, C, D: 627 - 1064 (UniProt: P49610)

PDB	External Database	Details
Arg 622	-	expression tag
Gly 623	-	expression tag
Ser 624	-	expression tag
His 625	-	expression tag
Met 626	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	199163.7
Non-Polymers*	Number of molecules	16
	Total formula weight	1681.6
All*	Total formula weight	200845.4

*Water molecules are not included.