4AV6

Crystal structure of Thermotoga maritima sodium pumping membrane integral pyrophosphatase at 4 A in complex with phosphate and magnesium

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	K(+)-STIMULATED PYROPHOSPHATE-ENERGIZED SODIUM PUMP	polymer	735	78217.1	2	UniProt (Q9S5X0) Pfam (PF03030)	THERMOTOGA MARITIMA	MEMBRANE-BOUND SODIUM-TRANSLOCATING PYROPHOSPHATASE, PYROPHOSPHATE-ENERGIZED INORGANIC PYROPHOSPHATASE, NA(+)-PPASE, TM-PPASE
2	C, D, J, K (A, B)	PHOSPHATE ION	non-polymer		95.0	4	Chemie (PO4)
3	E, F, G, H, L... (A, B)	MAGNESIUM ION	non-polymer		24.3	8	Chemie (MG)
4	I, P (A, B)	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)

Sequence modifications

A, B: 2 - 726 (UniProt: Q9S5X0)

PDB	External Database	Details
Met -8	-	expression tag
Arg -7	-	expression tag
Gly -6	-	expression tag
Ser -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
Leu 353	Val 353	engineered mutation
Gly 395	Ser 395	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	156434.3
Non-Polymers*	Number of molecules	14
	Total formula weight	652.5
All*	Total formula weight	157086.8

*Water molecules are not included.