4AU2

Crystal Structure of a Hsp47-collagen complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	SERPIN PEPTIDASE INHIBITOR, CLADE H (HEAT SHOCK PROTEIN 47), MEMBER 1, (COLLAGEN BINDING PROTEIN 1)	polymer	392	44283.7	4	UniProt (C7C419) Pfam (PF00079)	CANIS LUPUS FAMILIARIS (DOG)	HSP47
2	E, F, G, H, I... (E, F, G, H, I...)	15ER COLLAGEN MODEL PEPTIDE 15-R8	polymer	16	1301.5	6	UniProt (by SIFTS) (Q96A83)	HOMO SAPIENS
3	K, L, M, N, O... (A, B, C, D, E...)	water	water		18.0	234	Chemie (HOH)

Sequence modifications

A, B, C, D: 36 - 418 (UniProt: C7C419)

PDB	External Database	Details
Met 35	-	expression tag
Leu 419	-	expression tag
Glu 420	-	expression tag
His 421	-	expression tag
His 422	-	expression tag
His 423	-	expression tag
His 424	-	expression tag
His 425	-	expression tag
His 426	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	184943.7
All*	Total formula weight	184943.7

*Water molecules are not included.