4AT4
CRYSTAL STRUCTURE OF TRKB KINASE DOMAIN IN COMPLEX WITH EX429
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | BDNF/NT-3 GROWTH FACTORS RECEPTOR | polymer | 299 | 34351.7 | 1 | UniProt (Q16620) Pfam (PF07714) In PDB | HOMO SAPIENS (HUMAN) | GP145-TRKB, TRK-B, NEUROTROPHIC TYROSINE KINASE RECEPTOR TYPE 2, TRKB TYROSINE KINASE, TROPOMYOSIN-RELATED KINASE B |
| 2 | A | 1-[4-(4-aminothieno[2,3-d]pyrimidin-5-yl)phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea | non-polymer | 447.4 | 1 | Chemie (T6E) | |||
| 3 | water | water | 18.0 | 292 | Chemie (HOH) |
Sequence modifications
A: 543 - 838 (UniProt: Q16620)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ala 2 | - | expression tag |
| Met 3 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34351.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 447.4 | |
| All* | Total formula weight | 34799.1 |
