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4ASB

The structure of modified benzoquinone ansamycins bound to yeast N- terminal Hsp90

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
ATP-DEPENDENT MOLECULAR CHAPERONE HSP82polymer22024873.41UniProt (P02829)
Pfam (PF02518)
SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)82 KDA HEAT SHOCK PROTEIN, HEAT SHOCK PROTEIN HSP90 HEAT-INDUCIBLE ISOFORM
2B
(A)
(4E,6E,8S,9R,10E,12R,13R,14S,16R)-19-{[2-(dimethylamino)ethyl]amino}-13-hydroxy-8,14-dimethoxy-4,10,12,16,21-pentamethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamatenon-polymer630.81Chemie (8TO)
3C
(A)
waterwater18.029Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight24873.4
Non-Polymers*Number of molecules1
Total formula weight630.8
All*Total formula weight25504.2
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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