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4AS7

Eg5 complex 1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
KINESIN-LIKE PROTEIN KIF11polymer36841099.61UniProt (P52732)
Pfam (PF00225)
HOMO SAPIENS (HUMAN)KINESIN-LIKE PROTEIN 1, KINESIN-LIKE SPINDLE PROTEIN HKSP, KINESIN-RELATED MOTOR PROTEIN EG5, THYROID RECEPTOR-INTERACTING PROTEIN 5, TR-INTERACTING PROTEIN 5, TRIP-5
2B
(A)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
3C, D, E, N
(A)
CHLORIDE IONnon-polymer35.54Chemie (CL)
4F
(A)
COBALT (II) IONnon-polymer58.91Chemie (CO)
5G, H, I, J, K...
(A)
CADMIUM IONnon-polymer112.46Chemie (CD)
6M
(A)
N-(3-aminopropyl)-N-[(1R)-1-(3-benzyl-7-chloro-4-oxo-4H-chromen-2-yl)-2-methylpropyl]-4-methylbenzamidenon-polymer517.11Chemie (6LX)
7O
(A)
waterwater18.0258Chemie (HOH)
Sequence modifications
A: 1 - 368 (UniProt: P52732)
PDBExternal DatabaseDetails
Asp 133Ala 133engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41099.6
Non-Polymers*Number of molecules13
Total formula weight1819.5
All*Total formula weight42919.1
*Water molecules are not included.

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PDB entries from 2025-12-17

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