4AS1

Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and the benzoxaborole AN2679 in the editing conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	LEUCINE--TRNA LIGASE	polymer	880	99516.0	1	UniProt (P07813) Pfam (PF09334) Pfam (PF13603) Pfam (PF00133) Pfam (PF08264)	ESCHERICHIA COLI	LEUCYL-TRNA SYNTHETASE, LEURS
2	B (B)	TRNA-LEU5 (UAA ISOACEPTOR)	polymer	87	28167.6	1		ESCHERICHIA COLI
3	C (B)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	D, E (A, B)	water	water		18.0	402	Chemie (HOH)

Sequence modifications

A: 1 - 860 (UniProt: P07813)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	127683.6
Non-Polymers*	Number of molecules	1
	Total formula weight	24.3
All*	Total formula weight	127707.9

*Water molecules are not included.