4ARN

Crystal structure of the N-terminal domain of Drosophila Toll receptor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	TOLL RECEPTOR, VARIABLE LYMPHOCYTE RECEPTOR B.61 CHIMERA	polymer	279	31957.8	4	UniProt (P08953) UniProt (Q4G1L2) Pfam (PF13855) Pfam (PF11921)	DROSOPHILA MELANOGASTER (FRUIT FLY)	TOLL, VARIABLE LYMPHOCYTE RECEPTOR B
2	E (E)	alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		367.3	1	In PDB GlyTouCan (G86851RC)
3	F, H (F, H)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
4	G (G)	alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1203.1	1	In PDB GlyTouCan (G19179MO)
5	I, K, L, M, O (A, B, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)
6	J, N (A, B)	MALONATE ION	non-polymer		102.0	2	Chemie (MLI)
7	P, Q, R, S (A, B, C, D)	water	water		18.0	323	Chemie (HOH)

Sequence modifications

A, B, C, D: 28 - 228 (UniProt: P08953)

PDB	External Database	Details
Gly 300	-	expression tag
Glu 301	-	expression tag
Asn 302	-	expression tag
Leu 303	-	expression tag
Tyr 304	-	expression tag
Phe 305	-	expression tag
Gln 306	-	expression tag

A, B, C, D: 229 - 299 (UniProt: Q4G1L2)

PDB	External Database	Details
Ala 229	Asp 131	cloning artifact
Ser 230	Thr 132	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	127831.4
Branched	Number of molecules	4
	Total formula weight	2419.3
Non-Polymers*	Number of molecules	7
	Total formula weight	1310.1
All*	Total formula weight	131560.7

*Water molecules are not included.