4ARA
Mus musculus Acetylcholinesterase in complex with (R)-C5685 at 2.5 A resolution.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ACETYLCHOLINESTERASE | polymer | 548 | 60234.0 | 2 | UniProt (P21836) Pfam (PF00135) | Mus musculus (house mouse) | ACHE |
| 2 | C, N (A, B) | 4-(DIMETHYLAMINO)-N-{[(2R)-1-ETHYLPYRROLIDIN-2-YL]METHYL}-2-METHOXY-5-NITROBENZAMIDE | non-polymer | 350.4 | 2 | Chemie (C56) | |||
| 3 | D, F, G, O, Q... (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 9 | Chemie (PEG) | |||
| 4 | E, H, J, K, L... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 5 | I, M, V (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 6 | P (B) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) | |||
| 7 | Y (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 8 | AA, BA (A, B) | water | water | 18.0 | 628 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 543 (UniProt: P21836)
| PDB | External Database | Details |
|---|---|---|
| Ala 544 | - | expression tag |
| Thr 545 | - | expression tag |
| Glu 546 | - | expression tag |
| Ala 547 | - | expression tag |
| Pro 548 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 120468.0 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 3089.8 | |
| All* | Total formula weight | 123557.8 |
