4AQH
Plasminogen activator inhibitor type-1 in complex with the inhibitor AZ3976
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | PLASMINOGEN ACTIVATOR INHIBITOR 1 | polymer | 383 | 43232.5 | 3 | UniProt (P05121) Pfam (PF00079) | HOMO SAPIENS (HUMAN) | PAI, PAI-1, ENDOTHELIAL PLASMINOGEN ACTIVATOR INHIBITOR, SERPIN E1 |
| 2 | D, E, F (A, B, C) | TERT-BUTYL 3-[(4-OXO-3H-PYRIDO[2,3-D]PYRIMIDIN-2-YL)AMINO]AZETIDINE-1-CARBOXYLATE | non-polymer | 317.3 | 3 | Chemie (TB7) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 244 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 379 (UniProt: P05121)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 129697.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 952.0 | |
| All* | Total formula weight | 130649.7 |
