4ALM

Crystal structure of S. aureus FabI (P43212)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH]	polymer	282	31144.2	4	UniProt (Q7A6D8) Pfam (PF13561) UniProt (by SIFTS) (A0A0H3JLH9)	STAPHYLOCOCCUS AUREUS	ENR, ENOYL-ACP REDUCTASE
2	E, F, G, H, I... (A, B, C, D)	SULFATE ION	non-polymer		96.1	13	Chemie (SO4)
3	R, S, T, U (A, B, C, D)	water	water		18.0	214	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 256 (UniProt: Q7A6D8)

PDB	External Database	Details
Met -25	-	expression tag
Lys -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
Pro -17	-	expression tag
Met -16	-	expression tag
Ser -15	-	expression tag
Asp -14	-	expression tag
Tyr -13	-	expression tag
Asp -12	-	expression tag
Ile -11	-	expression tag
Pro -10	-	expression tag
Thr -9	-	expression tag
Thr -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
Ala 0	-	expression tag
Val 2	Leu 2	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	124577.0
Non-Polymers*	Number of molecules	13
	Total formula weight	1248.8
All*	Total formula weight	125825.8

*Water molecules are not included.