4ALK
Crystal structure of S. aureus FabI in complex with NADP and 5-ethyl- 2-phenoxyphenol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH] | polymer | 282 | 31144.2 | 8 | UniProt (Q7A6D8) | STAPHYLOCOCCUS AUREUS | ENR |
| 2 | BA, EA, I, L, O... (G, H, A, B, C...) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 8 | Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (71717786) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (165382010) | |||
| 3 | CA, FA, J, M, P... (G, H, A, B, C...) | 5-ETHYL-2-PHENOXYPHENOL | non-polymer | 214.3 | 8 | Chemie (E9P) PubChem (5274974) | |||
| 4 | AA, DA, K, N, Q... (F, G, A, B, C...) | GLUTAMIC ACID | non-polymer | 147.1 | 8 | Chemie (GLU) PubChem (611) PubChem (23327) PubChem (33032) | |||
| 5 | GA, HA, IA, JA, KA... (A, B, C, D, E...) | water | water | 18.0 | 1391 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 256 (UniProt: Q7A6D8)
| PDB | External Database | Details |
|---|---|---|
| Met -25 | - | expression tag |
| Lys -24 | - | expression tag |
| His -23 | - | expression tag |
| His -22 | - | expression tag |
| His -21 | - | expression tag |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| Pro -17 | - | expression tag |
| Met -16 | - | expression tag |
| Ser -15 | - | expression tag |
| Asp -14 | - | expression tag |
| Tyr -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Ile -11 | - | expression tag |
| Pro -10 | - | expression tag |
| Thr -9 | - | expression tag |
| Thr -8 | - | expression tag |
| Glu -7 | - | expression tag |
| Asn -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Tyr -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Val 2 | Leu 2 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 249153.9 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 8838.4 | |
| All* | Total formula weight | 257992.3 |
