4AEN

HLA-DR1 with covalently linked CLIP106-120 in reversed orientation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN	polymer	207	23167.9	1	UniProt (P01903) Pfam (PF00993) Pfam (PF07654)	HOMO SAPIENS (HUMAN)	MHC CLASS II ANTIGEN DRA
2	B (B)	HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DRB1-1 BETA CHAIN	polymer	199	23087.8	1	UniProt (P04229) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911)	HOMO SAPIENS (HUMAN)	MHC CLASS II ANTIGEN DRB1*1, DR-1, DR1
3	C (C)	HLA CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN	polymer	16	1865.5	1	UniProt (P04233)	HOMO SAPIENS (HUMAN)	HLA-DR ANTIGENS-ASSOCIATED INVARIANT CHAIN, IA ANTIGEN-ASSOCIATED INVARIANT CHAIN, II, P33, CD74
4	D, E (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5	F, G, H (A, B, C)	water	water		18.0	249	Chemie (HOH)

Sequence modifications

A: 1 - 192 (UniProt: P01903)

PDB	External Database	Details
Gly -14	-	expression tag
Gly -13	-	expression tag
Gly -12	-	expression tag
Gly -11	-	expression tag
Ser -10	-	expression tag
Gly -9	-	expression tag
Gly -8	-	expression tag
Gly -7	-	expression tag
Gly -6	-	expression tag
Ser -5	-	expression tag
Gly -4	-	expression tag
Gly -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

B: 1 - 198 (UniProt: P04229)

PDB	External Database	Details
Met 0	-	expression tag

C: 106 - 120 (UniProt: P04233)

PDB	External Database	Details
Met 105	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	48121.1
Non-Polymers*	Number of molecules	2
	Total formula weight	184.2
All*	Total formula weight	48305.3

*Water molecules are not included.