4ABI
Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (PtA)SFTI-1(1,14), that was 1,4-disubstituted with a 1,2,3- trizol to mimic a trans amide bond
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CATIONIC TRYPSIN | polymer | 223 | 23324.3 | 1 | UniProt (P00760) Pfam (PF00089) | BOS TAURUS (CATTLE) | BETA-TRYPSIN, ALPHA-TRYPSIN CHAIN 1, ALPHA-TRYPSIN CHAIN 2 |
| 2 | B (B) | PTA-SFTI INHIBITOR | polymer | 13 | 1533.8 | 1 | UniProt (Q4GWU5) BIRD (PRD_000842) | SYNTHETIC CONSTRUCT | |
| 3 | C (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | D, E, F (A) | DIMETHYLFORMAMIDE | non-polymer | 73.1 | 3 | Chemie (DMF) | |||
| 5 | G, H, I, J, K... (A) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 6 | N, O (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 7 | P, Q (A, B) | water | water | 18.0 | 250 | Chemie (HOH) |
Sequence modifications
B: 1 - 13 (UniProt: Q4GWU5)
| PDB | External Database | Details |
|---|---|---|
| Plf 8 | Pro 47 | SEE REMARK 999 |
| - | Pro 48 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 24858.1 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1096.1 | |
| All* | Total formula weight | 25954.2 |
