4AA4

P38ALPHA MAP KINASE BOUND TO CMPD 22

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	MITOGEN-ACTIVATED PROTEIN KINASE 14	polymer	365	42040.9	1	UniProt (Q16539) Pfam (PF00069)	HOMO SAPIENS (HUMAN)	MAP KINASE 14, MAPK 14, CYTOKINE SUPPRESSIVE ANTI-INFLAMMATORY DRUG-BINDING PROTEIN, CSAID-BINDING PROTEIN, CSBP, MAP KINASE MXI2, MAX-INTERACTING PROTEIN 2, MITOGEN-ACTIVATED PROTEIN KINASE P38 ALPHA, MAP KINASE P38 ALPHA, STRESS-ACTIVATED PROTEIN KINASE 2A, SAPK2A, P38ALPHA MAP KINASE
2	B (A)	N-[4-METHYL-3-[6-(4-METHYLPIPERAZIN-1-YL)-4-OXIDANYLIDENE-QUINAZOLIN-3-YL]PHENYL]FURAN-3-CARBOXAMIDE	non-polymer		443.5	1	Chemie (QC0)
3	C (A)	water	water		18.0	28	Chemie (HOH)

Sequence modifications

A: 2 - 360 (UniProt: Q16539)

PDB	External Database	Details
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	42040.9
Non-Polymers*	Number of molecules	1
	Total formula weight	443.5
All*	Total formula weight	42484.4

*Water molecules are not included.