4AA0

P38ALPHA MAP KINASE BOUND TO CMPD 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	MITOGEN-ACTIVATED PROTEIN KINASE 14	polymer	365	42040.9	1	UniProt (Q16539) Pfam (PF00069) In PDB	HOMO SAPIENS (HUMAN)	MAP KINASE 14, MAPK 14, CYTOKINE SUPPRESSIVE ANTI-INFLAMMATORY DRUG-BINDING PROTEIN, CSAID-BINDING PROTEIN, CSBP, MAP KINASE MXI2, MAX-INTERACTING PROTEIN 2, MITOGEN-ACTIVATED PROTEIN KINASE P38 ALPHA, MAP KINASE P38 ALPHA, STRESS-ACTIVATED PROTEIN KINASE 2A, SAPK2A, P38ALPHA MAP KINASE
2	A	N-[4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxidanylidene-quinazolin-3-yl]phenyl]-2-morpholin-4-yl-pyridine-4-carboxamide	non-polymer		539.6	1	Chemie (AA0)
3		water	water		18.0	307	Chemie (HOH)

Sequence modifications

A: 2 - 360 (UniProt: Q16539)

PDB	External Database	Details
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	42040.9
Non-Polymers*	Number of molecules	1
	Total formula weight	539.6
All*	Total formula weight	42580.5

*Water molecules are not included.