4A9C
Crystal structure of human SHIP2 in complex with biphenyl 2,3',4,5',6- pentakisphosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | PHOSPHATIDYLINOSITOL-3,4,5-TRISPHOSPHATE 5-PHOSPHATASE 2 | polymer | 316 | 36243.9 | 2 | UniProt (O15357) In PDB | HOMO SAPIENS (HUMAN) | INOSITOL POLYPHOSPHATE PHOSPHATASE-LIKE PROTEIN 1, INPPL-1, PROTEIN 51C, SH2 DOMAIN-CONTAINING INOSITOL-5'-PHOSPHATASE 2, SH2 DOMAIN-CONTAINING INOSITOL PHOSPHATASE 2, SHIP-2 |
| 2 | B | BIPHENYL 2,3',4,5',6-PENTAKISPHOSPHATE | non-polymer | 634.1 | 1 | Chemie (B5F) | |||
| 3 | water | water | 18.0 | 252 | Chemie (HOH) |
Sequence modifications
A, B: 419 - 732 (UniProt: O15357)
| PDB | External Database | Details |
|---|---|---|
| Ser 417 | - | expression tag |
| Met 418 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 72487.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 634.1 | |
| All* | Total formula weight | 73121.8 |
