4A7S
Structure of human I113T SOD1 mutant complexed with 5-Fluorouridine in the p21 space group
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, F) | SUPEROXIDE DISMUTASE [CU-ZN] | polymer | 153 | 15815.5 | 2 | UniProt (P00441) Pfam (PF00080) | HOMO SAPIENS (HUMAN) | SUPEROXIDE DISMUTASE 1, HSOD1 |
| 2 | C, J (A, F) | COPPER (II) ION | non-polymer | 63.5 | 2 | Chemie (CU) PubChem (27099) | |||
| 3 | D, K (A, F) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, F, I, L, M (A, F) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 5 | G, N (A, F) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) PubChem (175) | |||
| 6 | H, O (A, F) | 5-FLUOROURIDINE | non-polymer | 262.2 | 2 | Chemie (5UD) PubChem (21117591) PubChem (53799376) PubChem (44629859) PubChem (44630766) PubChem (45356917) PubChem (5270526) PubChem (7059460) PubChem (54669724) PubChem (57150717) PubChem (16072295) PubChem (60024157) PubChem (68206357) PubChem (1821) PubChem (9427) PubChem (101317) PubChem (1520351) PubChem (6712996) PubChem (7059458) PubChem (7059459) PubChem (7158513) PubChem (13066370) PubChem (13066372) PubChem (133688382) PubChem (142167589) PubChem (154186540) PubChem (173745165) | |||
| 7 | P, Q (A, F) | water | water | 18.0 | 463 | Chemie (HOH) |
Sequence modifications
A, F: 1 - 153 (UniProt: P00441)
| PDB | External Database | Details |
|---|---|---|
| Thr 113 | Ile 114 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31631.0 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1380.7 | |
| All* | Total formula weight | 33011.7 |
