4A7Q
Structure of human I113T SOD1 mutant complexed with 4-(4-methyl-1,4- diazepan-1-yl)quinazoline in the p21 space group.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, F) | SUPEROXIDE DISMUTASE [CU-ZN] | polymer | 153 | 15815.5 | 2 | UniProt (P00441) Pfam (PF00080) | HOMO SAPIENS (HUMAN) | SUPEROXIDE DISMUTASE-1, SUPEROXIDE DISMUTASE 1, HSOD1 |
| 2 | C, I (A, F) | 4-(4-METHYL-1,4-DIAZEPAN-1-YL)QUINAZOLINE | non-polymer | 242.3 | 2 | Chemie (4MQ) | |||
| 3 | D, E, F, J, K... (A, F) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 4 | G, L (A, F) | COPPER (II) ION | non-polymer | 63.5 | 2 | Chemie (CU) | |||
| 5 | H, M (A, F) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | O, P (A, F) | water | water | 18.0 | 477 | Chemie (HOH) |
Sequence modifications
A, F: 1 - 153 (UniProt: P00441)
| PDB | External Database | Details |
|---|---|---|
| Thr 113 | Ile 114 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31631.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1318.9 | |
| All* | Total formula weight | 32949.9 |
