4A7I
Factor Xa in complex with a potent 2-amino-ethane sulfonamide inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | FACTOR X LIGHT CHAIN | polymer | 96 | 10533.7 | 1 | UniProt (P00742) Pfam (PF00008) Pfam (PF14670) | HOMO SAPIENS (HUMAN) | FACTOR XA, COAGULATION FACTOR X, STUART FACTOR, STUART-PROWER FACTOR |
| 2 | B (B) | ACTIVATED FACTOR XA HEAVY CHAIN XA | polymer | 254 | 28550.6 | 1 | UniProt (P00742) Pfam (PF00089) | HOMO SAPIENS (HUMAN) | FACTOR XA, COAGULATION FACTOR X, STUART FACTOR, STUART-PROWER FACTOR |
| 3 | C (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | D (B) | 5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID [2-(1--ISOPROPYL-PIPERIDIN-4-YLSULFAMOYL)-ETHYL]-AMIDE | non-polymer | 394.0 | 1 | Chemie (A7I) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 206 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 39084.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 434.0 | |
| All* | Total formula weight | 39518.3 |
