4A6N
STRUCTURE OF THE TETRACYCLINE DEGRADING MONOOXYGENASE TETX IN COMPLEX WITH TIGECYCLINE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TETX2 PROTEIN | polymer | 398 | 44703.5 | 1 | UniProt (Q93L51) Pfam (PF01494) | BACTEROIDES THETAIOTAOMICRON | TETX |
| 2 | B, C, D (B, C, D) | TETX2 PROTEIN | polymer | 398 | 44703.4 | 3 | UniProt (Q93L51) Pfam (PF01494) | BACTEROIDES THETAIOTAOMICRON | TETX |
| 3 | E, I, O, S (A, B, C, D) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 4 | Chemie (FAD) | |||
| 4 | F, J, P, T (A, B, C, D) | TIGECYCLINE | non-polymer | 587.7 | 4 | Chemie (T1C) | |||
| 5 | G, H, K, L, M... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 11 | Chemie (SO4) | |||
| 6 | AA, X, Y, Z (D, A, B, C) | water | water | 18.0 | 210 | Chemie (HOH) |
Sequence modifications
A: 11 - 388 (UniProt: Q93L51)
B, C, D: 11 - 388 (UniProt: Q93L51)
| PDB | External Database | Details |
|---|---|---|
| Met -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Ser -7 | - | expression tag |
| Ser -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Ser 2 | - | expression tag |
| Gly 3 | - | expression tag |
| Leu 4 | - | expression tag |
| Val 5 | - | expression tag |
| Pro 6 | - | expression tag |
| Arg 7 | - | expression tag |
| Gly 8 | - | expression tag |
| Ser 9 | - | expression tag |
| His 10 | - | expression tag |
| Lys 272 | Glu 272 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Ser -7 | - | expression tag |
| Ser -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Ser 2 | - | expression tag |
| Gly 3 | - | expression tag |
| Leu 4 | - | expression tag |
| Val 5 | - | expression tag |
| Pro 6 | - | expression tag |
| Arg 7 | - | expression tag |
| Gly 8 | - | expression tag |
| Ser 9 | - | expression tag |
| His 10 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 178813.6 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 6549.6 | |
| All* | Total formula weight | 185363.2 |
