4A5B

Crystal structure of the C258S/C268S variant of Toxoplasma gondii nucleoside triphosphate diphosphohydrolase 1 (NTPDase1)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	NUCLEOSIDE-TRIPHOSPHATASE 2	polymer	611	68044.1	2	UniProt (Q27895) Pfam (PF01150) In PDB	TOXOPLASMA GONDII	NTPASE-II, NUCLEOSIDE TRIPHOSPHATE HYDROLASE 2, NUCLEOSIDE-TRIPHOSPHATASE II
2		water	water		18.0	247	Chemie (HOH)

Sequence modifications

A, B: 26 - 628 (UniProt: Q27895)

PDB	External Database	Details
Met 25	-	expression tag
Glu 629	-	expression tag
His 630	-	expression tag
His 631	-	expression tag
His 632	-	expression tag
His 633	-	expression tag
His 634	-	expression tag
His 635	-	expression tag
Ser 258	Cys 258	engineered mutation
Ser 268	Cys 268	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	136088.2
All*	Total formula weight	136088.2

*Water molecules are not included.