4A50
Crystal structure of human kinesin Eg5 in complex with 2-Amino-5-(3-methylphenyl)-5,5-diphenylpentanoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | KINESIN-LIKE PROTEIN KIF11 | polymer | 368 | 41055.6 | 1 | UniProt (P52732) Pfam (PF00225) | HOMO SAPIENS (HUMAN) | EG5, KINESIN-LIKE PROTEIN 1, KINESIN-LIKE SPINDLE PROTEIN HK KINESIN-RELATED MOTOR PROTEIN EG5, THYROID RECEPTOR-INTERACTING PROTEIN 5, TR-INTERACTING PROTEIN 5, TRIP-5 |
| 2 | B (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | (2S)-2-AMINO-5-(3-METHYLPHENYL)-5,5-DIPHENYLPROPANOIC ACID | non-polymer | 359.5 | 1 | Chemie (DQ6) | |||
| 5 | E (A) | (2R)-2-AMINO-5-(3-METHYLPHENYL)-5,5-DIPHENYLPROPANOIC ACID | non-polymer | 359.5 | 1 | Chemie (DQ7) | |||
| 6 | F (A) | water | water | 18.0 | 38 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41055.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1170.4 | |
| All* | Total formula weight | 42226.0 |
