4A11

Structure of the hsDDB1-hsCSA complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	DNA DAMAGE-BINDING PROTEIN 1	polymer	1159	129394.9	1	UniProt (Q16531) Pfam (PF10433) Pfam (PF03178)	HOMO SAPIENS (HUMAN)	DDB P127 SUBUNIT, DNA DAMAGE-BINDING PROTEIN A, DDBA, DAMAGE-SPECIFIC DNA-BINDING PROTEIN 1, HBV X-ASSOCIATED PROTEIN 1, XAP-1, UV-DAMAGED DNA-BINDING FACTOR, UV-DAMAGED DNA-BINDING PROTEIN 1, UV-DDB 1, XPE-BINDING FACTOR, XPE-BF, XERODERMA PIGMENTOSUM GROUP E-COMPLEMENTING PROTEIN, XPCE, COCKAYNE SYNDROME A PROTEIN
2	B (B)	DNA EXCISION REPAIR PROTEIN ERCC-8	polymer	408	45465.6	1	UniProt (Q13216) Pfam (PF00400)	HOMO SAPIENS (HUMAN)	COCKAYNE SYNDROME WD REPEAT PROTEIN CSA, UV-DAMAGED DNA-BINDING PROTEIN 1

Sequence modifications

A: 1 - 1140 (UniProt: Q16531)

PDB	External Database	Details
Met -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Val -11	-	expression tag
Asp -10	-	expression tag
Glu -9	-	expression tag
Asn -8	-	expression tag
Leu -7	-	expression tag
Tyr -6	-	expression tag
Phe -5	-	expression tag
Gln -4	-	expression tag
Gly -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Arg 0	-	expression tag

B: 1 - 396 (UniProt: Q13216)

PDB	External Database	Details
Gly 397	-	expression tag
Thr 398	-	expression tag
Ser 399	-	expression tag
Ala 400	-	expression tag
Trp 401	-	expression tag
Ser 402	-	expression tag
His 403	-	expression tag
Pro 404	-	expression tag
Gln 405	-	expression tag
Phe 406	-	expression tag
Glu 407	-	expression tag
Lys 408	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	174860.5
All*	Total formula weight	174860.5

*Water molecules are not included.