4A0Q
Activated Conformation of Integrin alpha1 I-Domain mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | INTEGRIN ALPHA-1 | polymer | 201 | 22363.2 | 2 | UniProt (P56199) Pfam (PF00092) | HOMO SAPIENS (HUMAN) | CD49 ANTIGEN-LIKE FAMILY MEMBER A, LAMININ AND COLLAGEN RECEPTOR, VLA-1, CD49A |
| 2 | C, D (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 184 | Chemie (HOH) |
Sequence modifications
A, B: 138 - 338 (UniProt: P56199)
| PDB | External Database | Details |
|---|---|---|
| Ser 139 | Cys 167 | engineered mutation |
| Thr 226 | Ile 254 | conflict |
| Ala 317 | Glu 345 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44726.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 48.6 | |
| All* | Total formula weight | 44775.1 |
