4A0P

Crystal structure of LRP6P3E3P4E4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 6	polymer	628	71170.1	1	UniProt (O75581) Pfam (PF00058) Pfam (PF14670)	HOMO SAPIENS (HUMAN)	LRP6, LRP-6
2	B, C (B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
3	D, E (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
4	F, G, M (A)	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
5	H, I, J (A)	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
6	K, L (A)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
7	N (A)	water	water		18.0	437	Chemie (HOH)

Sequence modifications

A: 629 - 1244 (UniProt: O75581)

PDB	External Database	Details
Glu 626	-	expression tag
Thr 627	-	expression tag
Gly 628	-	expression tag
Gly 1245	-	expression tag
Thr 1246	-	expression tag
Lys 1247	-	expression tag
His 1248	-	expression tag
His 1249	-	expression tag
His 1250	-	expression tag
His 1251	-	expression tag
His 1252	-	expression tag
His 1253	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	71170.1
Branched	Number of molecules	2
	Total formula weight	848.8
Non-Polymers*	Number of molecules	10
	Total formula weight	793.1
All*	Total formula weight	72812.0

*Water molecules are not included.