4R30
Structure of human laforin dual specificity phosphatase domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Laforin | polymer | 184 | 20997.3 | 4 | UniProt (O95278) Pfam (PF00782) | Homo sapiens (human) | Glucan phosphatase, Lafora PTPase, LAFPTPase |
| 2 | E, I, M, Q (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | F, G, H, J, K... (A, B, C, D) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 12 | Chemie (BME) | |||
| 4 | U, V, W, X (A, B, C, D) | water | water | 18.0 | 243 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 148 - 331 (UniProt: O95278)
| PDB | External Database | Details |
|---|---|---|
| Ser 266 | Cys 266 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 83989.4 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1321.8 | |
| All* | Total formula weight | 85311.2 |
