45AR
Crystal structure of C11 nanobody in complex with human MR1-5-OP-RU
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Major histocompatibility complex class I-related gene protein | polymer | 271 | 31711.7 | 1 | UniProt (Q95460) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (human) | MHC class I-related gene protein,Class I histocompatibility antigen-like protein |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C (C) | C11 nanobody | polymer | 128 | 14240.8 | 1 | Homo sapiens | ||
| 4 | D (A) | 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol | non-polymer | 316.3 | 1 | Chemie (2LJ) | |||
| 5 | E (C) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 6 | F, G, H (A, B, C) | water | water | 18.0 | 162 | Chemie (HOH) |
Sequence modifications
A: 1 - 270 (UniProt: Q95460)
B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Ser 261 | Cys 283 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 57831.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 339.3 | |
| All* | Total formula weight | 58171.1 |
