456C

CRYSTAL STRUCTURE OF COLLAGENASE-3 (MMP-13) COMPLEXED TO A DIPHENYL-ETHER SULPHONE BASED HYDROXAMIC ACID

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	MMP-13	polymer	168	18909.1	2	UniProt (P45452) Pfam (PF00413) In PDB	Homo sapiens (human)	COLLAGENASE-3
2	A, B	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	A, B	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4	A, B	2-{4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-TETRAHYDRO-PYRAN-4-YL}-N-HYDROXY-ACETAMIDE	non-polymer		425.9	2	Chemie (CBP)
5		water	water		18.0	103	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	37818.2
Non-Polymers*	Number of molecules	8
	Total formula weight	1193.6
All*	Total formula weight	39011.7

*Water molecules are not included.