44JD
KIR2DS1 bound to HLA-C*06:02 presenting the SV9 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen, C alpha chain | polymer | 276 | 32087.2 | 1 | UniProt (P10321) | Homo sapiens (human) | HLA-C,HLA-Cw,Human leukocyte antigen C |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) | Homo sapiens (human) | |
| 3 | C (C) | SV9 peptide | polymer | 9 | 1018.2 | 1 | synthetic construct | ||
| 4 | D (D) | Killer cell immunoglobulin-like receptor 2DS1 | polymer | 204 | 22549.3 | 1 | UniProt (Q14954) | Homo sapiens (human) | CD158 antigen-like family member H,MHC class I NK cell receptor Eb6 ActI |
| 5 | E, G (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) PubChem (753) | |||
| 6 | F (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | H, I, J, K (A, B, C, D) | water | water | 18.0 | 140 | Chemie (HOH) |
Sequence modifications
A: 1 - 276 (UniProt: P10321)
B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Asn 77 | Ser 101 | variant |
| Lys 80 | Asn 104 | variant |
| Trp 97 | Arg 121 | variant |
| Tyr 99 | Ser 123 | variant |
| Trp 147 | Leu 171 | variant |
| Glu 152 | Ala 176 | variant |
| Trp 156 | Leu 180 | variant |
| His 184 | Pro 208 | variant |
| Val 194 | Leu 218 | variant |
| Glu 253 | Gln 277 | variant |
| Val 261 | Met 285 | variant |
| Pro 267 | Gln 291 | variant |
| Arg 273 | Ser 297 | variant |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 67534.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 280.3 | |
| All* | Total formula weight | 67814.3 |
